Yasuhito Uezono Selected Research

Pain (Aches)

1/2024	Increased pain after palliative radiotherapy: not only due to cancer progression.
1/2022	Novel Opioid Analgesics for the Development of Transdermal Opioid Patches That Possess Morphine-Like Pharmacological Profiles Rather Than Fentanyl: Possible Opioid Switching Alternatives Among Patch Formula.
1/2022	A Successful Case of Switching Treatment from Ketamine to Methadone for Complex Neuropathic Pain.
9/2021	Inhibition of endothelin A receptor by a novel, selective receptor antagonist enhances morphine-induced analgesia: Possible functional interaction of dimerized endothelin A and μ-opioid receptors.
1/2021	Local Anesthetics Inhibit Transient Receptor Potential Vanilloid Subtype 3 Channel Function in Xenopus Oocytes.
1/2020	The Japanese herbal medicine Hangeshashinto enhances oral keratinocyte migration to facilitate healing of chemotherapy-induced oral ulcerative mucositis.
12/2017	Antidepressants inhibit Nav1.3, Nav1.7, and Nav1.8 neuronal voltage-gated sodium channels more potently than Nav1.2 and Nav1.6 channels expressed in Xenopus oocytes.
1/2017	Usefulness for the combination of G-protein- and β-arrestin-biased ligands of μ-opioid receptors: Prevention of antinociceptive tolerance.
1/2017	Relief from neuropathic pain by blocking of the platelet-activating factor-pain loop.
5/2016	Distinct TRPV1- and TRPA1-based mechanisms underlying enhancement of oral ulcerative mucositis-induced pain by 5-fluorouracil.

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Yasuhito Uezono Research Topics

Disease

36	Neoplasms (Cancer) 01/2024 - 08/2012
21	Pain (Aches) 01/2024 - 05/2004
13	Neuralgia (Stump Neuralgia) 07/2022 - 07/2013
12	Cachexia 10/2023 - 08/2012
11	Anorexia 10/2023 - 11/2012
7	Stomatitis 12/2022 - 09/2013
7	Hyperalgesia 01/2021 - 11/2008
6	Cancer Pain 01/2022 - 01/2014
5	Weight Loss (Weight Reduction) 10/2023 - 11/2012
5	Stomach Neoplasms (Stomach Cancer) 02/2022 - 01/2013
5	Intractable Pain 04/2020 - 03/2014
4	Mucositis 01/2021 - 05/2016
3	Vomiting 01/2024 - 09/2017
3	Chronic Pain 01/2021 - 11/2008
3	Constipation 01/2020 - 11/2012
3	Breast Neoplasms (Breast Cancer) 01/2020 - 12/2018
3	Peripheral Nervous System Diseases (PNS Diseases) 07/2019 - 01/2014
2	Nausea 01/2024 - 09/2017
2	Delirium 08/2023 - 11/2022
2	Emergence Delirium 08/2023 - 11/2022
2	Head and Neck Neoplasms (Head and Neck Cancer) 01/2022 - 06/2021
2	Cardiotoxicity 01/2021 - 01/2017
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 01/2017
2	Anxiety Disorders (Anxiety Disorder) 01/2020 - 01/2019
2	Inflammation (Inflammations) 01/2020 - 09/2014
2	Heart Failure 01/2020 - 02/2005
2	Atrophy 12/2018 - 11/2015
2	Fatigue 01/2018 - 11/2012
2	Dyspepsia (Indigestion) 09/2017 - 01/2015
2	Body Weight (Weight, Body) 01/2017 - 01/2014
2	Diarrhea 01/2017 - 09/2013
2	Ulcer 05/2016 - 01/2015
2	Hypesthesia (Numbness) 11/2015 - 11/2012
2	Ileus 04/2015 - 01/2015
2	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2015 - 01/2015
2	Gastroesophageal Reflux (GERD) 01/2015 - 11/2009
2	Bone Neoplasms (Bone Cancer) 10/2014 - 01/2014
1	Chronic Disease (Chronic Diseases) 10/2023
1	Frailty 10/2023

Drug/Important Bio-Agent (IBA)

10	Analgesics (Analgesic Drugs)IBA 09/2021 - 01/2014
9	liu-jun-zi-tangIBA 12/2018 - 08/2013
8	Opioid Analgesics (Opioids)IBA 07/2022 - 07/2013
8	Opioid Receptors (Opioid Receptor)IBA 07/2022 - 10/2012
6	Morphine (MS Contin)FDA LinkGeneric 07/2022 - 11/2008
6	Voltage-Gated Sodium ChannelsIBA 01/2021 - 03/2014
5	Cisplatin (Platino)FDA LinkGeneric 07/2020 - 08/2013
4	Fentanyl (Sublimaze)FDA LinkGeneric 01/2022 - 11/2008
3	Methadone (Dolophine)FDA LinkGeneric 01/2022 - 01/2018
3	EnzymesIBA 01/2020 - 01/2014
3	Proteins (Proteins, Gene)FDA Link 07/2019 - 01/2014
3	Adenosine Triphosphate (ATP)IBA 01/2017 - 03/2002
3	GhrelinIBA 01/2017 - 01/2014
3	gosha-jinki-ganIBA 11/2015 - 09/2013
3	Tramadol (K315)FDA LinkGeneric 10/2015 - 03/2002
3	NeuropeptidesIBA 09/2015 - 01/2007
3	Substance PIBA 04/2014 - 12/2010
2	Oxycodone (Oxycontin)FDA LinkGeneric 01/2024 - 11/2008
2	Yi-Gan SanIBA 11/2022 - 09/2013
2	Therapeutic UsesIBA 09/2021 - 01/2020
2	((3- methoxythiophen- 2- yl)methyl)((2- (9- (pyridin- 2- yl)- 6- oxaspiro(4.5)decan- 9- yl)ethyl))amineIBA 01/2021 - 01/2017
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 01/2017
2	Dinoprostone (PGE2)FDA Link 01/2020 - 09/2014
2	2- (1,3- dimethyl- 2,6- dioxo- 1,2,3,6- tetrahydro- 7H- purin- 7- yl)- N- (4- isopropylphenyl)acetamideIBA 07/2019 - 05/2016
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2019 - 12/2018
2	Pregnanolone (Allopregnanolone)IBA 05/2018 - 09/2014
2	Peptides (Polypeptides)IBA 01/2018 - 08/2013
2	AntiemeticsIBA 09/2017 - 04/2014
2	Platelet Activating FactorIBA 01/2017 - 01/2014
2	Fluorouracil (Carac)FDA LinkGeneric 01/2017 - 05/2016
2	1-Acylglycerophosphocholine O-Acyltransferase (1 Acylglycerophosphocholine O Acyltransferase)IBA 01/2017 - 01/2014
2	Acetic Acid (Vinegar)FDA LinkGeneric 05/2016 - 01/2015
2	Capsaicin (Zostrix)FDA Link 02/2016 - 01/2015
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 11/2015 - 01/2014
2	Lidocaine (Xylocaine)FDA LinkGeneric 03/2015 - 01/2015
2	Small Interfering RNA (siRNA)IBA 10/2014 - 01/2014
2	CatecholaminesIBA 02/2005 - 03/2002
1	Cytochrome P-450 CYP3AIBA 01/2024
1	Cytochrome P-450 CYP2D6 InhibitorsIBA 01/2024
1	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 01/2024
1	C-Reactive ProteinIBA 10/2023
1	Biomarkers (Surrogate Marker)IBA 10/2023
1	ramelteon (Rozerem)FDA Link 08/2023
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 07/2022
1	G Protein-Coupled Inwardly-Rectifying Potassium ChannelsIBA 07/2022
1	Interferon Type IIBA 02/2022
1	InterferonsIBA 02/2022
1	AlkaloidsIBA 02/2022

Therapy/Procedure

18	Drug Therapy (Chemotherapy) 01/2022 - 03/2014
11	Therapeutics 10/2023 - 12/2007
6	Ligation 07/2022 - 01/2017
6	Oral Administration 12/2020 - 02/2014
5	Kampo Medicine (Kampo) 01/2018 - 11/2012
4	Radiotherapy 01/2024 - 01/2016
3	Palliative Care (Palliative Therapy) 12/2022 - 11/2012
2	Analgesia 09/2021 - 03/2002
2	Spinal Injections 10/2014 - 01/2014
2	Transplantation 10/2014 - 01/2014
1	Polypharmacy 01/2024
1	Drug Tapering 01/2024
1	Gastrectomy 08/2023